Although numerous detergents have been developed for biochemical research, there is still a great need. For example, detergents are extensively used for membrane protein manipulation. Membrane proteins solubilized in conventional detergents are prone to denaturation and aggregation, rendering downstream characterization of these bio-macromolecules difficult. Although many efforts have been used to overcome the limited efficacy of conventional detergents, only a handful of novel detergents have so far proved very useful for membrane protein structural studies. Therefore, it is necessary to design and develop some excellent performance and novel structure detergents.
Alfa Chemistry's experience Ph.D. chemists specialize in novel detergents design. With our strong technical strength, Alfa Chemistry has established long-term cooperative relationship with numerous universities, enterprises and research institutions around the world, designing and synthesizing a variety of excellent detergents. Alfa Chemistry is pleased to work with you to solve your problems in scientific research. Please feel free to contact us for more details.
Design Strategy
According to customer's demands, Alfa Chemistry will design and synthesize high-efficiency detergent products based on the modification of existing excellent detergents. Currently, our general design strategy is as follows:
- Modification of the hydrophilic head or hydrophobic tail functional groups of detergents.
- Change the number of hydrophilic heads or hydrophobic tails of detergents.
- Change the spatial configuration of hydrophilic head or hydrophobic tail of detergents.
- Change the linking groups between hydrophilic head and hydrophobic tail of detergents.
Service Scope
Based on the deep research experience of detergent and its applications, Alfa Chemistry can assist in designing and synthesizing new detergents. Our service scope includes but not limited to:
- Anionic Detergents
- Zwitterionic Detergents
- Cationic Detergents
- Deuterated Detergents
- Non-ionic Detergents
- Special Detergents
※ The special detergents include neopentyl-based glycosides, fluorinated detergents, tripod detergents, seleniated detergents, peptide-based detergents, amphipols, branched detergents, various amphiphilic molecules, etc.
Service Content
Alfa Chemistry provides one-stop service for the design and synthesis of novel detergents, and responsibles for the whole process from experimental design to application performance evaluation. Our detergent design service includes the following content.
- Detergent design scheme
- Detergent synthesis (provide detailed synthesis record)
- Detergent structural characterization (Provide the data of high performance liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), nuclear magnetic analysis (NMR), etc.)
- Detergent physicochemical properties characterization (including purity, critical micelle concentration, aggregation number, micelle size, Krafft point, cloud point, hydrophilic-lipophilic balance (HLB) value, etc.）
- Detergent application performance evaluation
In addition, Alfa Chemistry will send you regular experiment progress reports and analytical test data to keep you abreast of your project progress. At the end of the project, we will provide you with a complete and detailed project report.
Why Choose Us?
Accurate and reliable
Advanced instruments and equipment make your project with reliable results.
Professional
Years of experience in the development of detergents.
Quality
Complete quality control and quality assurance system.
One-stop service
Provide technical support for the whole process from requirement analysis to project report.
Emphasis on communications
Timely updated, interactive real-time data review.
Competitive price
Short test cycle and competitive price compared to the peers.
Order Process
Our products and services are for research use only.
